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|TITLE||A Multi-Mechanism Skin Brightening Regimen Delivers Pigment Evening Benefits in an Ethnically Diverse Population|
|AUTHOR||Brenda L. Edison, BA, Barbara A. Green, RPh et al.|
|PUBLICATION||Poster presented at the 21st Congress of the European Academy of Dermatology & Venereology, Prague, Czech Republic, 27 – 30 September 2012|
A new brightening skincare regimen was developed to improve the complexion of facial skin by targeting multiple steps and pathways that affect pigmentation. The regimen consists of a facial cleanser, serum and lotion, which contain N-acetyl glucosamine* plus a variety of other benefit ingredients to collectively exfoliate pigmented areas, reduce tyrosinase activity and melanin production, and deliver an overall pigment evening effect.
N-acetyl glucosamine is known as NeoGlucosamine® in Exuviance products.
Overall improvement in skin pigmentation
User self-assessment on improvement during the 3 visits
Photography evidence of improvement with the use of the regimen
Visual grading and clinical photos showed
Self-assessment questionnaires confirmed that subjects noticed brighter skin tone, more even pigmentation, and less apparent brown spots
Marked improvement in pigmentation in standard lighting photographs and in cross-polarized photographs with melanin imaging applied to visualize hyperpigmented areas.